Pesticide Research Journal

SCOPUSWeb of Science
  • Year: 1998
  • Volume: 10
  • Issue: 2

Antifungal Activity of some 2-[N-(4-Fluorobenzoyl) glycyl] Amino 4,5-Disubstituted Thiazoles

  • Author:
  • Mukhtar Hussain Khan1, Manoj Kumar Srivastava, Nizamuddin
  • Total Page Count: 4
  • DOI:
  • Page Number: 254 to 257

#St. Andrew's College, Gorakhpur-273 001, U.P., India

Agro-chemical Research Laboratory Department of Chemistry, University of Gorakhpur, Gorakhpur-273 009, Uttar Pradesh, India

Abstract

A number of 2- amino thiazoles were acylated wiih ethylglycinate in acidic medium to obtain 2-glycilamino thiazoles, which were treated with 2-fluoro methylbenzoate to obtain title compounds (III). Their antifungal activity has been reporred against Aspergillus niger and Pyricularia oryzae. Based on screening data, attempts save ebeenade to highlight htructure-activity relationship.

Keywords

2-[N-(4-Fluorobenzoyl) glycyl] amino-4, 5-disubstituted thiazoles, glycinate, septacidin, cytotoxic, thiazoles