Reaction of Malonamide with 2-(1-Phenylethylideneamino) benzenethiols and Antifungal Potential of Products

Condensation of malonamide with 2-(1-phenylethylldeneamino) benzenethiols (I-VIII) resulted in the formation of solid products which were identified as 2-(1-phenylethylidene) malonamide and its derivatives (Ia-VIIa) on the basis of elemental analysis, m.m.p. determination and spectral studies. The results are at a variance as compared to similar condensation of malonamide with N-benzylideneaniline. The compounds Ia-VIIa were screened in vitro for their antifungal potential against Alternaria alternata, Fusarium oxysporum, Curvularia lunata and Myrothecium roridum. All the test compounds have shown promising activity against test fungi.