Pesticide Research Journal
SCOPUSWeb of Science
  • Year: 2012
  • Volume: 24
  • Issue: 2

Quantitative Structure Activity Relationship Study for Nematicidal Activity of O,O-Diaryl O-Ethyl Phosphorothionates

  • Author:
  • RL Gupta1,, A Bijul Lakshman1, D Prasad2
  • Total Page Count: 4
  • Page Number: 223 to 226

1Division of Agricultural Chemicals, Indian Agricultural Research Institute, New Delhi 110 012, India

2Division of Nematology, Indian Agricultural Research Institute, New Delhi 110 012, India

*Corresponding author E-mail: rlg_agch@iari.res.in

Online published on 19 June, 2014.

Abstract

The relationship between the structure of a series O,O-diaryl O-ethyl phosphorothionates and their nematicidal activity against Meloidogyne incognita and Rotylenchulus reniformis was analyzed using physicochemical parameters for hydrophobic, electronic and steric properties of the molecules by means of multiple regression analysis. The QSAR study has revealed that the nematicidal activity against both nematodes was dependent on the steric parameter of meta substituents. The STERIMOL parameters [ΣL(m)] against M. incognita and [ΣB1(m)] along with hydrophobic parameter RM against R. reniformis were found influencing the respective nematicidal activity.

Keywords

QSAR, phosphorothionates, organophosphorus compounds, nematicidal activity, Meloidogyne incognita, Rotylenchulus reniformis