Pesticide Research Journal

SCOPUSWeb of Science
  • Year: 2015
  • Volume: 27
  • Issue: 2

Acute Toxicity of Acetamiprid in Rats

  • Author:
  • Samiran Mondal1,, RC Ghosh1, Kamal Purohit2
  • Total Page Count: 6
  • DOI:
  • Page Number: 252 to 257

1Department of Veterinary Pathology, College of Veterinary Science and Animal Husbandry, Durg, Chhattisgarh, India

2Department of Veterinary Pathology, Rajasthan University of Veterinary and Animal Sciences, Rajasthan, India

Abstract

The pathology of acute acetamiprid toxicity in female wistar rats in reported. The approximate lethal dose (ALD) by oral route was found to be 506 mgkg−1 body weight. The toxicity signs were respiratory distress, hyperaesthesia, extensive tremors and terminal clonic convulsion, coma and death. At necropsy, severe haemorrhages in lungs and mild congestion in liver were noticed. Microscopically, congestion, haemorrhages and necrosis were found in liver, lungs, spleen and heart.

Keywords

Acetamiprid, lethal dose, rat