Method Validation, Dissipation and Decontamination of Flubendiamide Residues in Lettuce using LC/MS/MS

A method for determining flubendiamide residues in lettuce using LCMS/MS with negative electron spray ionization was developed and used for its residue analysis. Samples were extracted in acetonitrile and cleaned up by dispersive solid phase extraction with recovery of 70 to 120 per cent at RSD < 20 per cent. The residues dissipated on 25 and 30 d of application of flubendiamide at 24 and 48 g a.i. ha⁻¹ respectively on lettuce. Tamarind water washing was found very effective for decontamination of flubendiamide residues from iceberg lettuce. It removed 91.62 and 82.11 per cent of residues at the recommended and double the recommended doses.