Fungitoxicity and Quantitative Structure-Activity Relationships of S-Alkyl S,S-Diaryl Phosphorotrithioates

Twelve S-alkyl S,S-diaryl phosphorotrithioates have been tested for fungitoxicity in vitro against three soil borne fungi, Rhizoctonia solani, Rhizoctonia bataticola and Pythium aphanidermatum. S-methyl S,S-diphenyl phosphorotrithioate is found to be the most active except against R.bataticola in which case its p-methyl analogue showed slightly better activity. The activity of the most active compounds in this series is found to be at par with that of edifenphos. The quantitative structure-activity relationship study has revealed different structural requirements in terms of physico-chemical parameters for the activity against different fungi.