Department of Chemistry, Punjab Agricultural University, Ludhiana-141 004, Punjab, India
Online published on 3 November, 2011.
4-Thiazolidinones with unsubstituted N-phenyl ring and having hydroxy or thio group in ortho position of the N-phenyl ring have been synthesized by condensing thioglycolic acid and 2-mercaptopropionic acid with 4-methoxybenzalaniline, 4-methoxybenzal-2-thioaniline and 4-methoxybenzal-2-hydroxyaniline. These have been characterized on the basis of elemental analysis and spectral studies. Those having hydroxy group in the N-phenyl nucleus have been found to be effective fungicides, particularly against Alternaria alternata and Helminthosporium maydis by the spore germination inhibition technique.
Antifungal, thiazolidinones, methoxybenzal-anilines