Pesticide Research Journal
SCOPUSWeb of Science
  • Year: 1996
  • Volume: 8
  • Issue: 1

Effect of Substituents on the Antifungal Activity of 4-ThiazoIidinones derived from 4-Methoxybenzalanilines

  • Author:
  • M.R. Manrao, Monika Jolly, J.R. Sharma, P.S. Kalsi
  • Total Page Count: 4
  • Page Number: 13 to 16

Department of Chemistry, Punjab Agricultural University, Ludhiana-141 004, Punjab, India

Online published on 3 November, 2011.

Abstract

4-Thiazolidinones with unsubstituted N-phenyl ring and having hydroxy or thio group in ortho position of the N-phenyl ring have been synthesized by condensing thioglycolic acid and 2-mercaptopropionic acid with 4-methoxybenzalaniline, 4-methoxybenzal-2-thioaniline and 4-methoxybenzal-2-hydroxyaniline. These have been characterized on the basis of elemental analysis and spectral studies. Those having hydroxy group in the N-phenyl nucleus have been found to be effective fungicides, particularly against Alternaria alternata and Helminthosporium maydis by the spore germination inhibition technique.

Keywords

Antifungal, thiazolidinones, methoxybenzal-anilines