Future prospect of oral disintegration drug delivery system: A review

Many conventional dosage forms come in the market to achieve their therapeutic value as they administered via various routes. The dosage form is a imply used for the transport of drugs to a living body. To get the desired effect, the drug should be delivered to its site of action at such rate and concentration to acquire the maximum therapeutic effect and minimal adverse effect. The oral administration route is considered to be the most widely preferred route by patients, because of its convenience of administration and easy of manufacturing. Oral Dosage Forms, like orally disintegrating tablets (ODTs), Conventional tablets, Sublingual tablets, and Delay-release tablets. Orally disintegrating tablets differ from the traditional marketed tablets, in that they are designed to be dissolved on the tongue rather than swallowed whole. Oral disintegrating tablets (ODTs) are a novel dosage form that can be put on the tongue they disintegrate instantly, releasing the drug which dissolves or disperse in the saliva fluid, dissolved on the tongue inside 3-4 min or less, especially for geriatric and pediatric patients. By introducing into the mouth, these tablets dissolve or disintegrate in the mouth in the absence of additional water is a major throwback of conventional tablets. Nowadays, ODTs have received ever-increasing demand and this particular field has become a rapidly growing area in the pharmaceutical industry developments. ODTs are Quick absorption, rapid onset of action, and reduction in drug loss properties are the basic advantages of this dosage form. After the development of final formulations, evaluation of these tablets was done by like weight variation, hardness testing, friability tester, disintegration, the drug to polymer interaction, drug content, water absorption ratio, wetting time, and in-vitro drug release and stability studies.