Development and Evaluation of Transdermal patches of Piperine hydrochloride

The fundamentals of a successful pharmaceutical formulation depend on the delivery of the medicament to the target site at therapeutically relevant level, with negligible or minimum discomfort and side effects to the patient. Low dose maintenance therapy of Piperine HCl has the capability to reduce potential side effects and improved patient compliance which are more common with conventional drug delivery. The developed formulation of Piperine HCl is expected to improve the patient compliance, form better dosage regimen and provide maintenance therapy to patients suffering from inflammation and allergy. These promising results showed the feasibility of delivering Piperine HCl through transdermal matrix patch. The developed transdermal patches of Piperine HCl may prove to be a better alternative to conventional dosage forms in allergy as revealed by the results