Research Journal of Pharmaceutical Dosage Forms and Technology
  • Year: 2024
  • Volume: 16
  • Issue: 1

Advancing therapeutics with liposomal drug design: Harnessing the potential of liposomes for targeted drug delivery

  • Author:
  • Rupali Singh1, Sachi Sharma1, Sonia Awatar1, Dashain Purva1, Arjun Singh2,*
  • Total Page Count: 6
  • Published Online: Apr 26, 2024
  • Page Number: 119 to 124

1Department of Pharmacognosy, School of Pharmaceutical Sciences, Bhagwant University, Sikar Road, Ajmer, Rajasthan, 305004, India

2Department of Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, 19107, United States

*Corresponding Author E-mail: arjunphar@gmail.com

Online Published on 26 April, 2024.

Abstract

Liposomal drug design has emerged as a promising approach for targeted drug delivery. This article provides an overview of the principles and strategies involved in liposomal drug design, focusing on optimizing drug stability, controlled release, and enhanced therapeutic outcomes. The composition of liposomes, including the selection of lipids, plays a crucial role in determining their properties. Size and surface modifications of liposomes enable targeted drug delivery to specific tissues or cells. Liposomes offer versatility in drug encapsulation and controlled release kinetics, improving therapeutic efficacy while minimizing side effects. Incorporating targeting ligands onto liposome surfaces enhances their affinity for diseased sites, allowing for selective drug accumulation. Stability and manufacturing considerations are vital for the successful translation of liposomal drug delivery systems. Overall, liposomal drug design holds significant potential in revolutionizing drug delivery for improved treatment outcomes.

Keywords

Liposomal drug design, Liposomes, Lipids, Drug delivery, Controlled release