Formulation development and evaluation of topical herbal emulgel of turmeric

The benefits of topical drug delivery systems, which have been used for centuries, include the ability to deliver medications both quickly to the affected area where they are most effective and over an extended period of time. These systems lengthen the drug’s mean resident time and contact time. The formulation development and evaluation of topical herbal emulgel of turmeric medication administration is a goal of the current investigation.

Turmeric herbal emulgel were prepared using different concentration of Carbopol 934, as gelling agents and also different types of anti-preservatives such as propyl paraben, methyl paraben and evaluated the relevant parameters such as physical examinations, pH, viscosity, skin irritation test (patch test), extrudability (tube test), centrifugation test, spreadability, % drug content.

All formulations are neutral and viscosity of turmeric herbal emulgel was found in the acceptable limits. On physical evaluations were found to be optimum in terms spreadability, extrudability. Drug content of all formulations was found in between the 89.67 % to 98.34 % and TRM4 emulgel exhibiting the highest content of turmeric concentration. The results found that, the TRM4 are selected formulations proven that better wound healing as well as anti-inflammatory activities.

Type and concentration of polymers can have an impact on the drug permeability studies and physical-chemical characteristics as well increases in concentration of gelling agent so as increases in rheological properties of the developed turmeric emulgel, so which had excellent results and was suitable for possible therapeutic purposes.