Detailed review of shatdhaut ghrita as a base in moisturizing cream

Shatdhaut Ghrita (SDG), an Ayurvedic preparation of clarified butter (ghee) washed 100 times with water, has been traditionally used for its therapeutic properties in skin care. This review evaluates its efficacy and potential as a base in moisturizing cream formulations. The literature highlights SDG’s unique physicochemical properties, including enhanced bioavailability, stability, and penetration potential due to nanoscale particle size and emulsion formation. SDG’s composition—rich in short- and medium-chain fatty acids, antioxidants, and anti-inflammatory compounds—provides significant hydration, skin barrier repair, and wound healing benefits. The review also explores SDG’s compatibility with other excipients, showing its capacity to form stable emulsions and enhance the delivery of active pharmaceutical ingredients. Studies confirm its role in reducing transepidermal water loss (TEWL), alleviating conditions like eczema, psoriasis, and dry skin. Challenges in formulating with SDG, such as odor masking and standardization, are addressed with modern techniques.In conclusion, Shatdhaut Ghrita demonstrates excellent potential as a natural and effective base for moisturizing creams, warranting further clinical and formulation studies to standardize its use in modern cosmeceuticals.