Innovative drug delivery system oral fast dissolving film: A comprehensive review

In an effort to guarantee patient acceptability, safety, efficacy, and compliance, companies and researchers have been working on developing innovative drug delivery methods for the past few decades. The creation of new drugs takes a lot of money, effort, and time these days, but the trend is toward innovative medication delivery methods. Through a variety of methods, this delivery system facilitates both local and systemic drug response. The oral fast-dissolving film preparation (OFDFs) using this innovative method aids patients who are immobile, elderly, and pediatric. The goal of this review study is to provide information about potential therapeutic candidates and polymers for use in OFDFs, as well as specifics about the creation, information and examination of OFDFs. It also focuses on both positive aspects and drawbacks that have an impact on the film’s formulation. These films have good patient compliance, are pharmacoeconomic, and can be administered on their own. Oral fast dissolution films can be formulated using a variety of methods, the best of which being the solvent casting process. Buccal films are often made of hydrophilic polymers and other excipients, which dissolve fast and release the integrated APIs in a matter of seconds. There is potential for market and business development with oral fast dissolving films since they have many advantages in terms of accessibility, administration and withdrawal, retentivity, low enzymatic movement, economy, and high patient compliance. The mechanism of action, benefits, composition, formulation, evaluation, packaging and marketed formulations of oral fast dissolving films are highlighted in this prepared review. covers the topics around cutting-edge quick-solving methods as well.