Sharad Pawar College of Pharmacy, Wanadongri, Hingna Road, Nagpur 441110. Maharashtra. India
*Corresponding Author: Dinesh Pardhi Sharad Pawar College of Pharmacy, Wanadongri, Hingna Road, Nagpur-441110. Maharashtra. India. Phone No: +91-7104-236352. Fax No: +91-7104-235084 Email Id: dinshas_pharma@rediffmail.com
Online published on 19 March, 2013.
This review covers the detail aspects of Liquisolid formulation technique for solubility enhancement of poorly water soluble drugs. Over the years various methods are developed to enhance the drug solubility, liquisolid technique is one of promising the technique. The new fundamental mathematical model introduced by S. Spires and M. Bolton, 1999, helps to formulate the liquisolid systems. Formulation and development by liquisolid systems provides unprecedented opportunities for poorly water soluble drugs.
Liquisolid, Mathematical model