1Nootan Pharmacy College, S.K. Sahkar Vidhyadham, Near Kamana Crossing, Visnagar, Gujarat, PIN: 384315
2R.C. Patel Institute of Pharmaceutical Education and Research, Shirpur
*Corresponding Author: Svapnil Sanghavi Nootan Pharmacy College, S.K. Sahkar Vidhyadham, Near Kamana Crossing, Visnagar 384315 Gujarat Email: swapnil.pharmacist@gmail.com
Online published on 21 February, 2013.
Bilayer tablets provide one of the important design approaches where incompatible drugs, with different indication, and same drug with different release rate (e.g. IR and ER) can be incorporated in a single unit, or two incompatible drugs are needed to be provided in single dosage form. Bilayer tablets have several advantages over conventional tablets and few other dosage forms. The formulation and manufacturing of bilayer tablets face many challenges in terms of hardness, delamination, layer thickness and so on. This review highlights the material attributes, formulation design, process parameters that impact the performance, and manufacturability of the multilayer tablets.
