Research Journal of Pharmacognosy and Phytochemistry
Open Access
  • Year: 2009
  • Volume: 1
  • Issue: 1

In Vitro Cytotoxic Activity of Leaves of Abutilon indicum Linn. Against Ehrlich Ascites Carcinoma and Dalton's Ascitic Lymphoma Cell Line.

  • Author:
  • AV Bondre1,, SC Akare1, P Mourya1, AD Wanjari1, PS Tarte1, GV Paunikar1
  • Total Page Count: 3
  • Page Number: 72 to 74

1Department of Pharmacology, Guru Ramdas Khalsa Institute of Science and Technology, Jabalpur. (M.P) India

Department of Pharmacology, Bajiraoji Karanjekar College of Pharmacy, Sakoli, Dist. Bhandara. (M.S) 441802

*Corresponding Author: Mr. A V Bondre, Lecturer, Department of Pharmacology, Bajiraoji Karanjekar College of Pharmacy, Sakoli, Dist. Bhandara. (M.S) 441802 India, E-mail: amolbondre1984@rediffmail.com

Online published on 22 March, 2013.

Abstract

Alcohol and aqueous extracts from the leaves of Abutilon indicum Linn. Were investigating for their cytotoxic activity against EAC and DLA cell line. Various concentrations (10–200μg/ml) of each extract were treated in trypan blue method. Which involved determination of number of dead cells/total 100 cells counted gives the percentage of cytotoxicity was calculated. Both the extract exhibited significant cytotoxic activity at higher concentration of 200μg/ml. Distilled water used as a control.

Keywords

Abutilon indicum, cytotoxic activity, Ehrlich Ascites Carcinoma (EAC), Dalton's Ascitic Lymphoma (DLA)