Research Journal of Pharmacognosy and Phytochemistry
  • Year: 2009
  • Volume: 1
  • Issue: 2

Cytotoxic activity of Alphonsea sclerocarpa bark extract

  • Author:
  • Dasari Narendra Prasad
  • Total Page Count: 2
  • Page Number: 132 to 133

Dept. of Pharmacognosy, Nalanda College of Pharmacy, Cherlapally, Nalgonda, Andrapradesh, India

Online published on 22 March, 2013.

Abstract

Invitro cytotoxic activity of Alphonsea sclerocarpa has been investigated by tryphan blue dye exclusion method at various concentration on Ehlirich Ascites Carcinoma cells. The ethanolic extracts of Alphonsea sclerocarpa has showed the significant cytotoxic property by inhibiting the dye exclusion was evaluated by comparing with standard 5-Fluorouracil. The preliminary study indicates the ethanolic extract of Alphonsea sclerocarpa has significant cytotoxic property and suggests for further investigation for its antitumor and anticarcinogenic function in different models.

Keywords

Alphonsea sclerocarpa, Cytotoxic activity, EAC cells, 5fluorouracil