A Review on Euphorbiaceae plants for peptic ulcer

Peptic ulcer is one of the most common gastrointestinal disorders. The occurrence of peptic ulcer disease is attributed to the imbalance between aggressive factors like acid, pepsin and Helicobacter infection on one hand, and the local mucosa defense like bicarbonate, mucus secretion and prostaglandin synthesis on the other hand. A number of drugs including proton pump inhibitors and H2 receptor antagonists are available for the treatment of peptic ulcer, but these drugs has shown incidence of relapses, side effects, and drug interactions. Thus the development of new antiulcer drugs and the search for novel molecules has been extended to, herbal drugs that offer better protection and decreased relapse. Medicinal plants provide an effective and safer way in disease management. This review aims to compile data on plants from Euphorbiaceae family reported for their antiulcer properties.