1Department of Pharmacology, QIS College of Pharmacy, Vengamukkapalem, Ongole, Andhra Pradesh, India
2Department of Pharmaceutical Biotechnology, QIS College of Pharmacy, Vengamukkapalem, Ongole, Andhra Pradesh, India
3Department of Pharmaceutical Analysis, QIS College of Pharmacy, Vengamukkapalem, Ongole, Andhra Pradesh, India
4Department of Pharmacology, ASN Pharmacy College, Tenali, Andhra Pradesh, India
5Department of Pharmaceutics, QIS College of Pharmacy, Vengamukkapalem, Ongole, Andhra Pradesh, India
*Corresponding Author E-mail: revspharma@gmail.com
Online Published on 6 October, 2023.
Plant-based phytochemicals are promising antibiotics for treating microbial illnesses in humans. The purpose of the current study is to assess the antibacterial properties of an aqueous Cucumis melo extract against Bacillus subtilis and Escherichia coli. The Agar well diffusion method is initially used to assess the antibacterial activity of the fruit's aqueous extract against the gram’s positive B. subtilis and the gram’s negative organism E. coli. Results reveal that, in comparison to the control, the Cucumis melo aqueous fruit extract at two dose levels of 200 μg/ml and 400μg/ml significantly increases the zone of inhibition of microorganisms. Additionally, a very large zone of inhibition was seen at 400μg/ml dosage. The difference between the mean values of 200 and 400μg/ml was also encouraging. The aqueous extract exhibits a considerable dose, in conclusion.
Cucumismelo, Aqueous fruit extract, Antibacterial activity, Agar diffusion, Gram positive