Research Journal of Pharmacognosy and Phytochemistry
  • Year: 2023
  • Volume: 15
  • Issue: 1

Evaluation of antibacterial activity of aqueous extract of Cucumis melo

  • Author:
  • B. Revathi1,*, B. Sasidhar2, G. Raveendra Babu3, J. Divyalatha4, Ch. Devadasu3, D. Dhachinamoorthi5
  • Total Page Count: 4
  • Page Number: 1 to 4

1Department of Pharmacology, QIS College of Pharmacy, Vengamukkapalem, Ongole, Andhra Pradesh, India

2Department of Pharmaceutical Biotechnology, QIS College of Pharmacy, Vengamukkapalem, Ongole, Andhra Pradesh, India

3Department of Pharmaceutical Analysis, QIS College of Pharmacy, Vengamukkapalem, Ongole, Andhra Pradesh, India

4Department of Pharmacology, ASN Pharmacy College, Tenali, Andhra Pradesh, India

5Department of Pharmaceutics, QIS College of Pharmacy, Vengamukkapalem, Ongole, Andhra Pradesh, India

*Corresponding Author E-mail: revspharma@gmail.com

Online Published on 6 October, 2023.

Abstract

Plant-based phytochemicals are promising antibiotics for treating microbial illnesses in humans. The purpose of the current study is to assess the antibacterial properties of an aqueous Cucumis melo extract against Bacillus subtilis and Escherichia coli. The Agar well diffusion method is initially used to assess the antibacterial activity of the fruit's aqueous extract against the gram’s positive B. subtilis and the gram’s negative organism E. coli. Results reveal that, in comparison to the control, the Cucumis melo aqueous fruit extract at two dose levels of 200 μg/ml and 400μg/ml significantly increases the zone of inhibition of microorganisms. Additionally, a very large zone of inhibition was seen at 400μg/ml dosage. The difference between the mean values of 200 and 400μg/ml was also encouraging. The aqueous extract exhibits a considerable dose, in conclusion.

Keywords

Cucumismelo, Aqueous fruit extract, Antibacterial activity, Agar diffusion, Gram positive