1Dr. M.G.R. Educational and Research Institute, Dr. M. G. R University, Maduravoyal. Chennai-600 095, Tamil Nadu, India
2Sri Ramachandra Medical College and Research Institute, Chennai, Tamil Nadu, India
*Corresponding Author: K.G. Purushotham, Lecturer, Department of Industrial Biotechnology, Dr. M. G. R. Educational and Research Institute, Dr. M. G. R.University, Maduravoyal. Chennai-600 095, Tamil Nadu, India E-mail: purushoth_13@rediffmail.com, Ph.No.0988428831
Online published on 21 March, 2013.
Medicinal plants are potential of antimicrobial compounds. The present study deals with the antibacterial and antifungal activity of methanolic extracts of Tectona grandis (Verabinaceae) leaves were collected from the garden of Dr. M.G.R. University during May-June 2009, Chennai, India. Air-dried and extracted by methanol. The methanolic extract of Tectona grandis leaves were examined for antibacterial and antifungal activity by in vitro using the disc diffusion method, Minimum Inhibitory Concentration (MIC), Minimum Bactericidal Concentration (MBC) and Minimum fungicidal Concentration (MFC). Activity against Gram-positive (Streptococcus species (MTCC 389)), Gram-negative bacteria (Klebsiella pneumonia (MTCC 432), Psedomonas aeruginosa (MTCC 1688), Proteus mirabilis (MTCC 425), Escherichia coli, (MTCC 729), Salmonella typhimurium(MTCC 98))and fungal strains (Candida albicans, Cryptococcus neoformans, Aspergillus flavus, Aspergillus niger Aspergillus fumigatus Rhizopus sp. Trichophyton rubrum,Trichophyton gypseum and Trichophyton mentagrophytes) is discussed.
Antibacterial activity, Antifungal activity, Disc diffusion method, MIC, MBC, MFC, Tectona grandis
