Hypoglycemic Activity of Erythrina varigata in Alloxan Induced Diabetic Mice

Ethanolic leaf extract of Erythrina varigata was carried out using soxhlet apparatus. The extract was evaluated for preliminary phytochemical studies, acute toxicity studies and hypoglycemic activity. Acute toxicity study revealed that the ethanolic leaf extract even at high dose (2000mg/kg) produced no death and found to be safe. The hypoglycemic activity was evaluated in normal and alloxan induced diabetic mice. The chloroform fraction of the leaf extract was found to possess significant hypoglycemic activity when compared to standard Glibenclamide.