Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh-508 001, India
*Corresponding Author: D. Sathis Kumar, Assistant Professor, Nalanda College of Pharmacy, Nalgonda, Andhra Pradesh-508 001, India. Email: satmpdina@yahoo.co.in, Phone: +91 9966796051
Online published on 21 March, 2013.
The aim of the present study was to assess the effects of ethanolic extract of Physalis minima on the amylase, lipase and alpha glucosidase activity in vitro. Powder of whole plant of Physalis minima was extracted in ethanol and the extract was assayed for the measurement of inhibitory effects on activities of enzymes. The extracts rich in bioactive phytochemicals showed inhibitory activity on the amylase, lipase and alpha glucosidase, thus suggesting that extract might be useful in the treatment to limit dietary fat and glucose absorption and the accumulation of fat in adipose tissue. The extracts of Physalis minima may be safe, natural and cost effective for reducing fat and glucose absorption.
Physalis minima, amylase, lipase, alpha glucosidase
