Research Journal of Pharmacognosy and Phytochemistry
  • Year: 2010
  • Volume: 2
  • Issue: 3

Evaluation of in vitro Anti-Oxidant Activity of Premna integrifolia Linn. Mant. Root

  • Author:
  • RH Gokani1, MA Rachchh1, SK Lahiri2, DD Santani3, MB Shah2,
  • Total Page Count: 4
  • Page Number: 196 to 199

1Dept. of Pharmacognosy, S.J. Thakkar Pharmacy College, Rajkot, India

2Dept. of Pharmacognosy, L. M. College of Pharmacy, Ahmedabad, India

3Dept. of Pharmacology, L. M. College of Pharmacy, Ahmedabad, India

*Corresponding Author: Dr. Rina H. Gokani “Shrikunj” 3-Archana park, B/H Krishna complex. University Road, Rajkot-360005. Gujarat E-mail: rinu42003@yahoo.co.in, rinman13@gmail.com

Online published on 21 March, 2013.

Abstract

Root of Premna integrifolia known under common name Arni/Agnimantha which is an important constituent of well known formulation, Dashmularistha used for various ailments. In the present study methanolic extract of the roots was evaluated for its in-vitro antioxidant activity using the anti radical, superoxide scavenging, anti lipid peroxidation, hydroxyl radical scavenging and nitric oxide scavenging, assays. The extract showed significant anti-oxidant activity in all the assays. The study scientifically demonstrated the use of P. integrifolia as a potential source of natural antioxidant.

Keywords

P. integrifolia, Verbanaceae, Anti-oxidant activity