1Department of Pharmacognosy, MES, College of Pharmacy, Sonai, 414105, Tal. Newasa, Dist. Ahmednagar, (M.S.), India
2Department of Pharmaceutical Sci. RTM, Nagpur University, Nagpur (M.S.), 440010, India
3P.W. Colleges of Pharmacy, Yavatmal, (M.S.), 445001, India
*Corresponding Author: Chandrashekhar Damodar Khadse (Research scholar) Department of Pharmacognosy, MES College of Pharmacy, Sonai, 414105, Tal. Newasa, Dist. Ahmednagar (M.S.), India. E-mail: khadsecd@rediffmail.com Mob. No. +919921357845 Phone No. 02427-230848
Online published on 21 March, 2013.
The purpose of this study is to search for a natural excipient that can be used as alternative in the formulation of pharmaceutical suspensions. Present study was carried out to evaluate suspending properties of mucilage of seeds Linnum usitatisimum Lin. with those of tragacanth and Acacia at concentration range of 1.0–4.0% w/v in calcium carbonate suspension. Evaluation parameters like sedimentation profile, redispersibility, and pH were compared with calcium carbonate (2.0%w/v) suspension prepared by using acacia and tragacanth gum as standard suspending agent. Suspension prepared with linseed mucilage was found a superior suspending agent than acacia and comparable with tragacanth. Linseed mucilage can be used as an effective alternative in the formulation of pharmaceutical suspensions.
suspending agent, Linnum usitatisimum, flax seed, mucilage
