Research Journal of Pharmacognosy and Phytochemistry

  • Year: 2010
  • Volume: 2
  • Issue: 6

Anti-Ulcer Effects of Ipomoea aquatica forsk Leaves against Gastric Ulcers in Rats

  • Author:
  • P. Muthukumaran1,, K. Pattabiraman2
  • Total Page Count: 4
  • Page Number: 471 to 474

1P.G. Dept.of Biochemistry, Meenakshmi Chandrasekaran Arts and Science College, Pattukkottai 614 601, Thanjavur, Tamilnadu, India

2Department of Siddha Medicine, Faculty of Science, Tamil University, Vakaiyur, Thanjavur -613 010, Tamilnadu, India

*Corresponding Author: P. Muthukumaran Lecturer, P.G. Dept. of Biochemistry Meenakshmi Chandrasekaran Arts and Science College, Pattukkottai 614 601, Thanjavur, E mail: muthubabi_p@yahoo.co.in

Online published on 21 March, 2013.

Abstract

The anti ulcer effects of aqueous, chloroform and ethanol extracts prepared from the Ipomoea aquatica forsk leaves was evaluated in rats employing the pylorus ligation, stress induced and aspirin induced models. The parameters taken to assess anti ulcer activity were volume of gastric juice, free acidity, total acidity and ulcer index. The results indicated that chloroform extract significantly (p<0.001) decreased the volume of gastric acid secretions, free acidity and total acidity and ulcer index.

Keywords

Ipomoea aquatica forsk Antiulcer effect, Pylorus ligation, Aspirin, Stress