The Erode College of Pharmacy, Tamilnadu
*Corresponding Author: Mr. S. Manokaran, M. Pharm., Dept. of Pharmacognosy, The Erode College of Pharmacy, Veppampalayam, Vallipurathan Palayam (PO), Erode – 638 112. Tamilnadu, India. Mobile No: +919626056858 E-mail: msellimuthu@gmail.com
Online published on 21 March, 2013.
Hepato-toxicity is a common toxicity happening during the treatment of chronic disease like tuberculosis, diabetics. Prunus persica belongs to Rosaceae is a plant growing in temperate region has laxative, sedative, anticancer property and also consist of glycosides, flavonoids, anthocyanins, vitamins. It also posses hepato-protactent property. To prove the activity scientifically the ethanolic extract of Prunus persica was studied against paracetamol induced hepatotoxicity in albino rats. The extract when evaluated at dose of 100mg/kg was found to significantly reduce the elevated levels of serum lysosomal enzyme Sgpt, Sgot, Alp and Bilirubin when compared with standard silymarin.
Prunus persica, paracetamol, albino rats, serum enzymes