1C. U. Shah College of Pharmacy, S.N.D.T Women's University, Santacruz (West), Mumbai-400049, India
2ICMR Advanced Centre of Reverse Pharmacology in Traditional Medicine, Kasturba Health Society, Vile Parle (West), Mumbai-400 056, India
*Corresponding Author: Dr. Pratima A. Tatke, Associate Professor, C. U. Shah College of Pharmacy, S.N.D.T Women's University, Mumbai-400 049. India. Phone: +91 9920685857 Email: patatke@gmail.com
Online published on 21 March, 2013.
The present paper discuss the antioxidant activity of methanol extracts of commonly available three garlic varieties in India using various in vitro methods Viz, DPPH assay, total reducing power and TBARS assay. The results were analyzed statistically by regression method and IC50 values were calculated for all the extracts. The amounts of total phenolics and flavonoids were also determined for each extract of garlic. All the extracts exhibited good free radical scavenging activity. Antilipid peroxidation activity of all garlic varieties was comparable to standard antioxidant, ascorbic acid. Methanol extract of single bulb variety of garlic exhibited better antioxidant activity among all three garlic varieties. The study provides evidence for the beneficial role of garlic. The antioxidant activity of garlic extracts will effectively contribute to the prevention of various chronic conditions and also confirms its ancient traditional claims.
Garlic, Allium sativum, antioxidant, free radical scavenging
