Prin. K.M. Kundnani College of Pharmacy, Cuffe Parade, Colaba, Mumbai
*Corresponding Author: Ms. Shivani Watak, Prin. K.M. Kundnani College of Pharmacy, Cuffe Parade, Colaba, Mumbai. Email: watak_shivani@rediffmail.com, Mob. 9220842415
Online published on 8 February, 2013.
Phenolic compounds are metal chelator, it is interesting to investigate Their metal-chelating property, which stimulates our interest to evaluate Zn(II)chelating ability and the effect of Zn(II) on its radical-scavenging activity by theoretical calculation. It was revealed that Phenolic compound could efficiently sequester Zn(II) and the Zn(II)-Phenolic compound complexes were more active than the parent compound in scavenging radicals by donating proton or electron. Therefore, Phenolic compounds are a multipotent agent, with the activities of scavenging ROS, blocking Aβ aggregation and chelating metal ions
metal chelator, antioxidant, Phenolic compounds
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