Anti-Inflammatory Activity of Some Indigenous Sudanese Plants

Three medicinal plant extracts from Sudan, used in traditional medicine, were investigated for their anti-inflammatory activity against carrageenan-induced inflammation. The present study is an endeavor to evaluate the anti-inflammatory activity of methanolic extract of Solenostemma argel leaves, Hordeum vulgare grains and Ziziphus spina-christi fruits. The anti-inflammatory activity of the extracts was evaluated using the carrageenan-induced Wister rats edema model. Among the extracts, the S. argel extract at a dose of 100 mg/kg body weight exhibited an inhibition of inflammation after 3hr (22%) of carrageenan administration. The most significant inhibition was revealed by the Z. spina-christi after 1 hr. (55%), at a dose of 100 mg/kg body weight, whilst the extract of H. vulgare grains had no effect on the edema at the same concentration.