Research Journal of Pharmacology and Pharmacodynamics
  • Year: 2009
  • Volume: 1
  • Issue: 3

Cytotoxic Activity of Glocihdium zeylanicum Leaf Extract

  • Author:
  • Srivalli Tripuramallu, Srikanth Sunkara, Venkata Ramana Reddy. Maram
  • Total Page Count: 2
  • Page Number: 145 to 146

Gitanjali College of Pharmacy, Cheeryal, Keesara Mandal, Rangareddy District

*Corresponding Author: Srivalli Tripuramallu, Gitanjali College of Pharmacy, Cheeryal, Keesara Mandal, Rangareddy District. E.mail: srivalli_gupta@yahoo.com

Online published on 20 March, 2013.

Abstract

In vitro cytotoxic activity of Glocihdium zeylanicum has been investigated by tryphan blue dye exclusion method at various concentrations on Ehlirich Ascites Carcinoma cells. The ethanolic extracts of Glocihdium zeylanicum has showed the significant cytotoxic property by inhibiting the dye exclusion was evaluated by comparing with standard 5-Fluorouracil. The preliminary study indicates the ethanolic extract of Glocihdium zeylanicum has significant cytotoxic property and suggests for further investigation for its antitumor and anticarcinogenic function in different models.

Keywords

Glocihdium zeylanicum, Cytotoxic activity, EAC cells, 5-fluorouracil