Hydro alcoholic extract of Punica granatum for anthelmintic activity

The present study was aimed to investigate the anthelmintic potential of Hydro alcoholic Punica granatum Peel extract on Indian earth-worm Pheretima posthuma. Three concentrations (100, 150, 200 mg/ml) of extract were studied in activity which involved the determination of time of paralysis (vermifuge) and time of death (vermicidal) of the worms. Albendazole (20 mg/ml) in same concentration as those of extract was included as standard reference and normal saline water with 0.5% w/v CMC as control. The extracts exhibited significant anthelmintic activity at a concentration of 150, 200 mg/ml. Peak activity was exhibited by the Hydro alcoholic extract at a concentration of 200 mg/ml, respectively dose-dependent action and inhibition of spontaneous motility (paralysis) and death of earthworms Findings of the present investigations confirms that, the ethnomedicinal claim of anthelmintic activity of this plant is genuine.