Research Journal of Pharmacology and Pharmacodynamics
  • Year: 2021
  • Volume: 13
  • Issue: 1

Analysis of blood pressure, lipid profile and hematological biomarkers in men addicted to tobacco chewing

  • Author:
  • Atoussi Ouidad1, Chetehouna Sara1, Boulaares Islam1, Guemari Imane Yousra1, Derouiche Samir12,
  • Total Page Count: 4
  • Page Number: 1 to 4

1Department of Cellular and Molecular Biology, Faculty of Natural and Life Sciences, University of Echahid Hamma Lakhdar El Oued, El Oued, 39000, Algeria

2Laboratory of Biodiversity and Application of Biotechnology in the Agricultural Field, University of El Oued, El-Oued39000, Algeria

*Corresponding Author E-mail: dersamebio@gmail.com

Online published on 4 May, 2021.

Abstract

Our study aimed to evaluate the effect of chewing tobacco consumption on lipid profile, blood pressure and hematological biomarkers in chewers men adult. The experimentation is carried out on 22 voluntary individuals were divided into two groups; the first group of healthy individuals (controls) and the second group was tobacco chewers. All the volunteers were subjected to estimate the blood pressure, lipid profile, biochemical and hematological parameters. The finding results showed there are a significant increase (P<0.05) in each of systolic and diastolic blood pressure in chewers when we compare to the control subjects. Also, the level of TC, TG, VLDL-c, LDL-c and Atherogenic index (AI) are highly significant raised (P<0.01). However, the biochemical parameters no changed in chewers group as compared to the control one. Concerning erythrocyte line, there were a significant decrease (P<0.01) of RBC, Hgb, HTC while significant increase of PLT level (p<0.05) in tobacco chewers compared to the controls. But for leukocyte line we didn't notice any significant change in chewers compared to controls. In conclusion the present study revealed that the tobacco consumption in chewing form may be induce sever change in lipid profile which cause the alteration in blood pressure that increased the cardiovascular risk for this population. Additionally, tobacco consumption may be lead to anemia symptoms in its consumers.

Keywords

Tobacco, Chewers, Lipid profile, Blood pressure, Hematological biomarkers