Research Journal of Pharmacology and Pharmacodynamics
  • Year: 2023
  • Volume: 15
  • Issue: 2

Comparison of Anti-Inflammatory Property between Conventional drugs and Ayurvedic Preparations-an in vitro study

1Department of Pharmacology, Sri Venkateswara College of Pharmacy, Madhapur, Hyderabad, Telangana, India

2Department of Pharmacology, SSJ College of Pharmacy, Hyderabad, Telangana, India

*Corresponding Author E-mail: anu-manas0108@gmail.com

Online Published on 06 October, 2023.

Abstract

Numerous medicinal products are used in the traditional medical systems in India. An alternative medicine for the treatment of various diseases is getting more popular now a days. Many medicinal plants provide relief of symptoms comparable to that of obtained from allopathic medicines. Therefore, agents of natural origin with very little side effects are required as substitute chemicals therapeutics. The Ayurvedic preparations include Rheumartho and Rheumatil (200µg/ml, 300µg/ml, and 450µg/ml) was investigated for anti- inflammatory effects in in vitro method. Inhibition of albumin denaturation was adopted for the in-vitro anti-inflammatory activity. The ayurvedic drugs were effective in inhibiting the heat induced haemolysis at different concentrations. The results revealed that ayurvedic preparations (Rheumatil and Rheumartho) at concentration 200 µg/ml, 300µg/ml reduces the inflammation significantly (P<0.01) compared to the control. From this study, it was concluded that ayurvedic preparations (Rheumartho and Rheumatil) possess anti- inflammatory with lesser side effects and more beneficial effects.

Keywords

HRBC, Anti-inflammatory, Albumin denaturation, Ayurvedic preparations