Phytochemical Analysis and Antidepressant Activity of Elaeocarpus serratus Extracts in Experimental Models of Depression in Mice

Elaeocarpus serratus tropical flowering tree belong to the family elaeocarpaceae. The fruit of the tree is frequently consumed by people and is also used in folk medicine. The Antidepressant activity of leaf extracts of E. serratus was evaluated using Forced swim test and Tail suspension test. In the present investigation, phytochemical analysis revealed the presence of Flavonoids, Carbohydrates, Proteins, Tannins Saponins, Triterpenoids, Steroids, Glycosides and Alkaloids. The ethanol and aqueous extracts of E. serratus at high dose 400mg/kg showed moderate significance and low dose 200mg/kg showed less significance in antidepressant activity.