Research Journal of Pharmacology and Pharmacodynamics
  • Year: 2024
  • Volume: 16
  • Issue: 3

Alzheimer’s Disease: An Outline of Therapeutic Interventions by different Approaches

Department of Pharmacology, Karnataka College of Pharmacy, Bengaluru - 560064, Karnataka, India

*Corresponding Author E-mail: dyuthi81977@gmail.com

Online Published on 23 April, 2025.

Abstract

A neurodegenerative condition called Alzheimer’s disease (AD) impairs neurocognitive function and hinders the growth of mental ability. This neuropathological condition presents with neurodegeneration, neuronal loss, and the development of neurofibrillary tangles and Ab plaques. Dementia, neuronal loss, and the development of neurofibrillary tangles and Ab plaques are the hallmarks of this neuropathological disorder. Such a medication is not able to cure Alzheimer’s disease. The drug that’s now available just treats symptoms. Two major obstacles to research are the blood-brain barrier, which reduces the effectiveness of treatments, and the incomplete comprehension of the ethology of Alzheimer’s disease. Stem cell-based therapy has been seen as a novel, reliable and successful restoration technique to treat AD since the condition is complex and has not gotten much attention. The latest advances in nanotechnology occasionally offer proactive treatment chances that can help get over limitations. In this overview, we concentrate on the causes of AD and the various methods used to treat them.

Keywords

Alzheimers disease, Amyloid hypothesis, Genetic risk factors, Tau hypothesis, Neuroinflammation, Biomarkers, Alzheimers disease treatment, Stem cell therapy