Evaluation of in-vitro anti-spasmodic activity of methanolic extract of bark part of Albizia odoratissima by using chicken Ileum

The current study has focused on the pharmacological study of anti-spasmodic activity of bark part of Albizia odoratissima of the family Fabaceae. Albizia odoratissima is a deciduous tree which is having a number of potential medicinal uses. It was used as Anti-inflammatory, Antioxidant, Digestive health, respiratory disease & Skin Disorders etc. The evaluation of phytochemicals of bark part indicates the presence of Alkaloid, Anthraquinone glycoside, tannins, Terpenoids etc. The antispasmodic effect was tested on chicken ileum by inducing spasms with acetylcholine. The impact of watery extract and methanolic extract on acetylcholine-induced spasms in chicken ileum was evaluated using atropine, a standard antispasmodic drug. The effects of watery extract and methanolic extracts on acetylcholine-induced spasms in chicken intestine were assessed with atropine, a recognized antispasmodic medication. In the chicken ileum, the impact of steroidal activities on the muscarinic and Histamine receptors, combined with the antioxidant properties of Albizia odoratissima, plays a key role in the overall observed effects. Therefore, in this study, the plant Albizia odoratissima demonstrates a strong and favourable muscle-relaxant activity.