1Rajendra Institute of Technology and Sciences, Sirsa (Haryana)
2Chitkara School of Pharmaceutical Sciences, Chitkara University, Barotiwala (HP)
3NCRD's Sterling Institute of Pharmacy, Navi Mumbai
*Corresponding Author: Mr. Pankaj Rakha, Rajendra Institute of Technology and Sciences, Sirsa (Haryana) E-mail: pankajrakha@yahoo.co.in
Online published on 20 March, 2013.
Gastroesophageal reflux disease (GERD) is primarily a motility disorder. Escape of gastric contents into the esophagus occurs as a consequence of an incompetent gastroesophageal barrier. This barrier is weakened in the presence of an abnormally functioning Lower Esophageal Sphincter (LES). This review is focused on the epidemiology, pathophysiology and treatments of gastro-oesophageal reflux disease.
Reflux, proton pump inhibitors, H2 receptor antagonists, radiofrequency
