Research Journal of Pharmacology and Pharmacodynamics
  • Year: 2010
  • Volume: 2
  • Issue: 2

Evaluation of Anti-inflammatory Activity of leaf extract of Morinda citrifolia L. (Noni)

  • Author:
  • Khuntia Tapas Kumar1,, D. S. Panda2, S. Khuntia3
  • Total Page Count: 3
  • Page Number: 194 to 196

1Department of Pharmacology, K.L.R. Pharmacy College, Paloncha, Andhra Pradesh, India

2Department of Pharmaceutics, Institute of Pharmacy and Technology, Salipur, Orissa

3College of Pharmaceutical Sciences, Puri, Orissa

*Corresponding Author: Khuntia Tapas Kumar, Department of Pharmacology, K.L.R. Pharmacy College, Contractors colony, Paloncha, A.P., INDIA, E-mail: tapaskhuntia_mpharm@yahoo.com, Phone No: +91 9393798381

Online published on 20 March, 2013.

Abstract

Morinda citrifolia L. (Noni) (Rubiaceae) has been used in folk remedies by Polynesians, Indians for over 2000 years, and is reported to have a broad range of therapeutic effects, including antibacterial, antiviral, antifungal, antitumor, analgesic, hypotensive, and immune enhancing effects. Petroleum ether extract of leaves of Morinda citrifolia L. (Noni) was studied for its invivo anti-inflammatory potential using carageenen induced rat paw edema and cotton pellet induced granuloma methods. The results of the study indicate that the petroleum ether extract possess significant anti-inflammatory activity at doses 150mg/kg and 300mg/kg.

Keywords

Immune enhancing, antiviral, antifungal, antitumor, granuloma