1Dept of Pharmacology, Maratha Mandal's College of Pharmacy, Belgaum, India
2Dept of Pharmacology, K.L.E's Institute of Dental Sciences, Bangalore, India
*Corresponding Author: Sambrekar S.N. Professor and HOD, Dept of Pharmacology, Maratha Mandal's College of Pharmacy, Belgaum. 560010. Karnataka, India. Phone: 9448230416, e-mail: sumney_anita@rediffmail.com
Online published on 20 March, 2013.
Extracts of Embelia tsjeriam-cottam Fruits were investigated for antiinflammatory activity with acute and chronic models. In the doses of 200 mg kg−1exhibited significant (P < 0.001) anti-inflammatory activity in all the models tested. The alcohol extract of Embelia tsjeriam-cottam at 200 mg kg−1 showed maximum inhibition of paw volume 1.21 ± 0.1 in carrageenaninduced rat paw edema while the standard drug Diclofenac it was 1.18 ± 0.1 after 6 hrs of carrageenan injection. In the chronic inflammatory model alcoholic extract inhibited the granuloma weight by 35.50%, whereas the Diclofenac inhibited 46.18%.
Anti-inflammatory activity, carrageenan induced rat paw, cotton pellet induced granuloma, Embelia tsjeriam-cottam
