Research Journal of Pharmacology and Pharmacodynamics
  • Year: 2012
  • Volume: 4
  • Issue: 1

Screening of Anti-inflammatory Potential of Berberis coriaceae Leaves by HRBC Membrane Stabilization

  • Author:
  • Amit Roy1,, Ram Kumar Sahu2
  • Total Page Count: 2
  • Page Number: 5 to 6

1Columbia Institute of Pharmacy, Tekari, Raipur (C.G.), India

2Oriental College of Pharmacy, Patel Nagar, Bhopal (M.P.), India

*Corresponding Author: Dr. Amit Roy Professor and Principal, Columbia Institute of Pharmacy, Pharmacy, Tekari, Raipur (C.G.), India Email. wakratund@gmail.com

Online published on 21 February, 2013.

Abstract

The present study was undertaken to screen anti-inflammatory activity of alcohol and aqueous extracts of leaves from Berberis coriaceae against HRBC membrane stabilization. The prevention of hypotonicity induced HRBC membrane lysis was taken as a measure of the anti-inflammatory activity. Both the extracts showed a biphasic effect on the membrane stabilization. Their activities are comparable to that of the standard drug diclofenac sodium. However their activities decreased with time.

Keywords

Berberis coriaceae, HRBC, Diclofenac sodium