1School of Pharmaceutical Science & Research, Berhampur University, Berhampur, Odisha –760007
2School of Pharmaceutical Sciences, SOA University, Bhubaneswar, Odisha-754030
*Corresponding Author: S. K. Sahu, School of Pharmaceutical Science & Research, Berhampur University, Berhampur, Odisha –760007. E-mail- sujitkumar_2008@yahoo.com
Online published on 21 February, 2013.
Crude ethanolic extract of Mollugo pentaphylla Linn. (family-Aizoaceae) was investigated for diuretic and laxative activity in albino rats at 200 and 400 mg/kg p.o. Which was compared with standard drugs Furosemide (10mg/kg, p.o.) and Agar agar (300mg/kg, p.o.) respectively. The extract was found to produce significant diuretic as well as laxative activity at dose 400 mg/kg. The plant was also found to possess the phytoconstituents like carbohydrates, alkaloids, gums, saponins, flavanoids, tanins and steroids.
Mollugo pentaphylla, Acute toxicity study, Diuretic activity, Laxative activity
