Anti-inflammatory Action of Ougeinia oojeinensis (Roxb.) Hochr. Bark by HRBC Membrane Stabilization

The ethanolic and aqueous extracts of the bark of Ougeinia oojeinensis (Roxb.) Hochr (Fabaceae) known in Hindi as Tinsa, were screened for anti-inflammatory activity. The dried powdered drug was successively extracted with several solvents and out of these the ethanolic and aqueous extract was selected for present study due to presence of several photochemical in them. The prevention of hypotonicity induced HRBC membrane lysis was taken as a measure of the anti-inflammatory activity. Both the fraction showed a biphasic effect on the membrane stabilization. Their activities are comparable to that of the standard drug diclofenac sodium. However their activities decreased with time.