Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2008
  • Volume: 1
  • Issue: 4

Validated Spectroscopic Method for Estimation of Aceclofenac from Tablet Formulation

  • Author:
  • Rohit Shah, Chandrakant Magdum, Shital Kumar Patil, Dhanya Kumar Chougule, Nilofar Naikwade
  • Total Page Count: 3
  • Page Number: 430 to 432

Appasaheb Birnale College of Pharmacy, Sangli South Shivajinagar, Sangli416416. Maharashtra

*Corresponding Author E-mail: rohitrshah@yahoo.co.in

Abstract

Aceclofenac is a non steroidal anti-inflammatory drug with good analgesic and anti-rheumatic properties. Various methods for analysis of the same are available but are time consuming and expensive. Here we have developed a new, precise and simple UV spectrophotometric method for estimation of aceclofenac from tablet formulation. The drug obeyed the Beer's law and showed good correlation. It showed absorption maxima at 273 nm; in phosphate buffer pH 7.4. The linearity was observed between 0 – 20 mcg/mL. The results of analysis were validated by recovery studies. The recovery was more than 99%. The method was found to be simple, accurate, precise, economical and robust.

Keywords

Aceclofenac, UV–Vis Spectrophotometry, Recovery