Department of Pharmaceutical Chemistry, College of Pharmacy, Mother Theresa Post Graduate and Research Institute of Health Sciences, (A Government of Puducherry Institution), Indira Nagar, Gorimedu, Puducherry-06
A series of some novel 1, 2-disubstituted benzimidazole derivatives were synthesized by condensing 2substituted benzimidazole with various primary amino compounds. The purity of synthesized compounds was confirmed by melting point determination and thin layer chromatography method. The chemical structure of synthesized compounds was characterized using IR-Spectroscopy. The compounds were docked against the target enzyme Biotin Carboxylase. The compounds showed significant binding energy (PA4, PA5, PA6, PA10) were evaluated for their
2-Substituted Benzimidazoles, Biotin Carboxylase, Anti-bacterial activities, Staphylococcus aureus, Salmonella typhi..
