Research Journal of Pharmacy and Technology

SCOPUS
  • Year: 2017
  • Volume: 10
  • Issue: 2

Anti-Proliferative activity of Chlorophyllin from Phyllanthus Emblica L. against MCF-7 and Vero Cell line

1Assistant Professor, Department of Biotechnology, Mohamed Sathak College of Arts and Science, Sholinganallur, Chennai-119

2Associate Professor, Department of Biotechnology, Vels Institute of Science Technology and Advanced Studies (VISTAS), Vels University, Pallavaram, Chennai

Abstract

Chlorophyllin refers to any one of a group of closely related water-soluble salts that are semi-synthetic derivatives of chlorophyll. It is most common form is sodium copper derivative used as a food additive and in alternative medicine. In this study sodium copper chlorophyllin was extracted from Phyllanthus emblica, a medicinal plant and estimated by visible spectrophotometer and further characterized by TLC, IR, NMR and GC-Mass Chromatographic techniques and studied the anticancer activity against MCF-7 cell line and Vero cell line. Result shows that Chlorophyllin of Phyllanthus emblica has good anticancer activity for breast cancer cell line by using MTT assay.

Keywords

Chlorophyllin, Thin Layer Chromatography, MTT assay