1Reader, Department of Oral and Maxillofacial Surgery, Saveetha Dental College, Saveetha University, 162, Poonamallee High Road, Velappanchavadi, Chennai, 600077, Tamil Nadu, India
2Undergraduate Student, Department of Oral and Maxillofacial Surgery, Saveetha Dental College, Saveetha University
*Corresponding Author E-mail: santhoshsurgeon@gmail.com
Online published on 7 July, 2018.
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor-β (TGF-β) super family. BMP3 was originally purified from bone as osteogenin, which induces osteogenic differentiation. Bone morphogenic protein 3 inhibits osteoblast differentiation and is thus a negative regulator of bone density. Bone morphogenic protein 3 plays a role in fracture healing, mechanical loading of the skeleton, development, and osteoporosis. This article reviews the various functions of bone morphogenic protein 3 and its clinical applications.
Bone morphogenic protein 3, BMP 3, bone formation, cartilage, protein, receptor, fracture healing
