Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2018
  • Volume: 11
  • Issue: 5

Detection of hemolysin and gelatinase in uropathological Escherichia coli

1Bachelor of Dental Surgery, Department of Microbiology, Saveetha Dental College and Hospital, Chennai, Tamilnadu, India

2Assistant Professor, Department of Microbiology, Saveetha Dental College and Hospital, Chennai, Tamilnadu, India

*Corresponding Author E-mail: marlog7494@gmail.com

**gopu.myco@gmail.com

Online published on 21 August, 2018.

Abstract

Urinary tract infection(UTI) is a major public health concernin developing countries. Most UTIs are caused by E.coli, accounting for up to 90% of community acquired UTIs.

A total of 20 clinical isolates of uropathological E.coli(UPEC) were subjected for antibiotic sensitivity pattern and virulence assay such as hemolysin and gelatinase production.

100% of our isolates were hemolysin producers, whereas none of the isolates were positive for gelatinase production.

Hemolysin might play a crucial role in initiation of UTI in hospitalized individuals. Drug resistance can also be the factor for the treatment failure cases.

Keywords

Hemolysin, Gelatinase, Enterotoxigenic, uropathology