Department of Chemistry, College of Science, University of Babylon, Iraq
A series of Schiff's bases and their novel derivatives (Oxazepines) have been synthesized, 4-hydroxy-3methoxy benzaldehyde (vanillin) was condensed with different amines to produce the Schiff's bases in the presence of glacial acetic acid as a catalyst or KOH, novel five 1, 3-oxazepine derivatives have been synthesized through reaction of Schiff's bases with succinic anhydride and maleic anhydride using acidic catalyst. The identification was performed using, FT-IR and1H-NMRspectroscopies. The synthesized1, 3-oxazepine derivatives were biologically screened against gram positive (
1, 3-oxazepine, Vanillin, Schiff's bases, anti-bacterial activity, disk diffusion method, cycloaddition
