Drug Utilization Evaluation of Coronary Artery Disease in a Tertiary Care Hospital in Punjab

The main aim of this study was to evaluate the drug utilization of coronary artery disease patients.

This prospective study was carried out over the duration of nine months between August 2017-April 2018 in Guru Gobind Singh medical college and hospital, Faridkot, Punjab, India. All Inpatients who were diagnosed with coronary artery disease were included in the study and written consent was taken from them. The data was collected in a specially designed data collection form and analyzed using IBM SPSS Version 25.

Among 390 patients, the majority of them, 59% were males. The mean age of the study population was found to be 59.89 years. Most of the patients were from urban locality 61.5%. The average duration of stay of patients in the hospital was 4.21±1.53 days. Majority of the patients were found to be Sikh religion 48.5%. Only 4% of patients were given a single drug and 44% more than six drugs. The most common drug related problem was class duplication 32. Only 35% prescribed drugs had Irrational dose. When compared to WHO core prescribing indicators 19.16% drugs administered were fixed dose combinations, 46.66% were drugs from the National Essential Medicine List, 78.50% of drugs were prescribed by brand names and 49% of drug therapy had encounters with an antibiotic. Average no. of Drugs per prescription were 8.53.

Male gender, urban locality, age group of 51–60 was found to be more prevelent among the study population. Majority of the patients were given Polypharmacy. It was found that dosing or frequency prescribed in 26% cases was irrational. Most common drug related problems was class duplication.