Research Journal of Pharmacy and Technology
SCOPUS
  • Year: 2019
  • Volume: 12
  • Issue: 1

Synthesis, Characterization and Antimicrobial Activities of Some New Amino-Pyrimidine Derivatives.

1Research Scholar, School of Applied SciencesSinghania UniversityPacheri Bari, Jhunjhunu (Raj), India

2Department of Chemistry, Agra College, Agra, U.P, India

3Head Department of Chemistry, B K Birla Institute of Engineering and Technology, Pilani, Rajasthan, India

*Corresponding Author E-mail: ykgbkbiet@rediffmail.com, ykgbkbiet@yahoo.com, ykgbkbiet123@gmail.com

Online published on 16 March, 2019.

Abstract

In the present work, an efficient synthesis of some new Amino-Pyrimidine Derivatives has been created through response of chalcones of cyclic imides and guanidine nitrate in presence of neutral alumina. The new synthesized amino-pyrimidines showed synergistic significant activities against Candida albicans and Aspergillus nigerfungal strains.

Keywords

Amino-pyrimidines, chalcones, antimicrobial activity